PRODUCTS

Seal the Deal with an Intact Biological Graft.

BIODESIGN DURAL GRAFT

The Biodesign Dural Graft is intended for use as a dura substitute for repairing dura mater.

Nexsis Biosciences is the exclusive U.S. and Canadian provider of Sales Support for the Cook Biotech Biodesign Dural Graft

Biodesign® Dural Graft

ORDER NUMBER	REFERENCE PART NO.	INSTRUCTIONS FOR USE	SIZE (CM)
G31090	C-DUR-4x7	Learn More	4 x 7
G32437	C-DUR-2x3	Learn More	2 x 3
G31091	C-DUR-7x10	Learn More	7 x 10
G31092	C-DUR-7x20	Learn More	7 x 20

Order No: G31092
Reference Part No: C-DUR-7×20
Instructions for Use
Size (cm): 7 x 20

Order No: G31091
Reference Part No: C-DUR-7×10
Instructions for Use
Size (cm): 7 x 10

Order No: G31090
Reference Part No: C-DUR-4×7
Instructions for Use
Size (cm): 4 x 7

Order No: G32437
Reference Part No: C-DUR-2×3
Instructions for Use
Size (cm): 2 x 3

CASE STUDY #1

Biodesign Biologics Become You, No Permanent Material Left Behind

Biodesign biologic grafts are derived from small intestinal submucosa (SIS), a naturally occurring, intact extracellular matrix. SIS acts as a scaffold that allows host cells to infiltrate and remodel into vascularized tissue, leaving no permanent material in the patient’s body.

Product Features:

Manufactured in the US
Biologic xenograft made from porcine SIS
Non-cross-linked, non-dermis
Easily hydrated in the operating room
No special orientation or sidedness
Off-the-shelf graft that does not require special storage
Translucent once hydrated to easily visualize suture positioning
Does not require AATB tissue tracking
MRI safe

REFERENCE

Bejjani GK, Zabramski J; Durasis Study Group. Safety and efficienty of porcine small intestine small mucosa dural subsititute: results of a prospective multicenter study and literature review. J Neurosurg. 2007; 106(6):1028-1033

CASE STUDY #2

Retrospective Study Confirms Performance of Biodesign Grafts for Transcranial Dura Mater Repair

Purpose: The purpose of this study was to assess the real-world performance of the Biodesign graft as a dura substitute for repairing dura mater. This report specifically analyzes a subset of patients who underwent trans-cranial dura mater repairs with the Biodesign graft.

Endpoints: The primary endpoint was the postoperative integrity of the graft 1 month after surgery as defined by the lack of need to return to the operating room to repair a cerebrospinal fluid (CSF) leak. Secondary endpoints included postoperative graft integrity at the last available patient follow-up visit (with a minimum of 6 months’ follow-up) and the assessment of adverse events for normal, widespread use of the graft in the short-term postoperative period. Data were collected from 81 patients at Toronto Western Hospital, Toronto, Ontario, Canada.

Results: Eighty-one patients were included in the final analysis.

Benefits of Biodesign grafts in dura mater repair

No donor site required and no donor site morbidity
Easy to handle and suture, allowing for a watertight seal
Provides the strength required for a durable repair
Functions as a scaffold for the ingrowth of host cells for a natural repair
Produces little to no scar formation
Does not swell upon hydration
Provides a leak-free repair

CONCLUSION

This study confirms the safety and effectiveness of using Biodesign grafts for dura mater repair when used in a transcranial approach. No unexpected or serious adverse events were reported among the 81 patients in the study, and no patients examined were returned to the operating room for a postoperative CSF leak.