SIS has been used used to manage multiple types of wounds, including burns, diabetic ulcers, venous ulcers, and trauma wounds. Surgical applications include dura repair, hernia repair, fistula repair, otologic repair, and soft-tissue reinforcement.
The open, three dimensional structure of the ECM permits cells and capillaries to grow into the matrix. Cells deliver nutrients and secret collagen gradually renewing and reinforcing the site with the patient’s own tissue until completely healed.
As pioneers in ECM technologies, our partner develops and continuously improves proprietary processing and manufacturing methods to retain the inherent properties of our naturally occurring source materials.
This convergence of nature and technology results in medical-grade devices that help patients overcome serious medical conditions while leaving no permanent material behind.
SIS acts as a scaffold material to support the population of the ECM with patient-derived cells
SIS is gradually replaced by the patient’s own tissue and cells
The patient’s own collagen gradually matures into a stable structure that has long-term strength but is entirely the patient’s own